The DART SVP features the automated sampling stage that permits repetitive scanning across a single sample or set of samples as shown below.


Up to 10 tablets can be placed on the sampling stage. Selecting the Temperature Profile ...

In order to investigate the dynamic range of to DART for Tablet analysis we used the Temperature Profiling Method to analyze both the Daytime and Nighttime Caplets. Using the 350C profile as the optimum temperature for simultaneous generation of ions, ...

So called matrix effects often dictate that samples be analyzed by LC/MS since their presence with analyte leads to inefficient ionization or formation of adducts. The effect of various solvents on DART efficiency is show here using the common standard...

Discovery Analytical Chemistry and Medicinal Chemistry, Wyeth Research, Collegeville, Pennsylvania 19426, and IonSense, Saugus, Massachusetts 01906

Direct analysis in real time (DART) is a novel ionization technique that provides for the...

Simplify reaction monitoring over time with instant feedback. Here we compare LC/MS data showing the relative concentration of the precursor and product over time vs. results obtained without the LC separation using DART. The distribution of ions in th...

Nighttime Caplet
– Acetaminophen
• 325 mg/caplet
– Phenylephrine HCl
• 5 mg/caplet
– Chlorpheniramine
Maleate
• 2 mg/caplet

10% Tylenol Powder in Metal
• TIC irregular...